Train services connecting Bletchley and Bedford will restart next week.
Service operator London Northwestern Railway (LNR) has confirmed services on the Marston Vale Line will return as national lockdown measures ease further.
Rail replacement buses had been operating on the line during the latest period of lockdown, with passenger numbers extremely low.
With non-essential shops, gyms and community centres preparing to open their doors, LNR will reintroduce a limited number of trains during the morning and afternoon peak periods from Monday-Saturday.
Services will return from Monday 12 April, with returning services selected in consultation with local colleges and community groups.
Rail replacement buses will continue to run at other times.
Passengers are being reminded of the latest Government advice to minimise journeys where possible and to avoid the busiest times if travelling.
Lawrence Bowman, customer experience director for London Northwestern Railway, said, “With lockdown measures easing further, now is the right time to reintroduce trains to the Marston Vale Line to help our passengers travel with confidence.
“We encourage passengers using the train to maintain social distancing on board and remind all customers that everyone aged over 11 must wear a face covering by law, unless exempt on medical grounds.”
Passengers are advised to check their train times before setting out.